Requesting pricing for pharmacogenomics (PGx) testing of the following genes. They have clinical utility and can support PGx testing if abnormalities are found and the patient is on or being considered for relevant meds:
Gene Implication Supports PGx Need if:
CYP2D6 — Poor/ultrarapid metabolizers of antidepressants, opioids, beta blockers: Patient is on SSRIs, opioids, or cardiac meds
CYP2C19 — Affects metabolism of SSRIs and clopidogrel: Patient has history of depression, heart disease
SLCO1B1 — Statin sensitivity: Patient is on statins or has hyperlipidemia
HLA-B15:02* — Carbamazepine/oxcarbazepine risk (SJS/TEN): Patient has seizure history or mood disorders